Sped 8500 basic clinical practicum in speech-language pathology (2 credits) These courses are designed to provide the speech-language pathology candidate with experiences of a clinical nature prior to intensive participation in practica in the educational, medical, clinical, and/or other rehabilitation settings.

MCGH267-FM_i-xii.qxd 4/6/13 9:31 AM Page i a LANGE medical book Clinical Neuroanatomy Twenty-Seventh Edition Stephen G. Waxman, MD, PhD Bridget Marie Flaherty Professor of Neurology, Neurobiology, & Pharmacology Director, Center for Neuroscience & Regeneration Research Yale University School of Medicine New Haven, Connecticut New York Chicago San Francisco Lisbon London Madrid Mexico City Milan New Delhi San Juan Seoul Singapore Sydney Toronto MCGH267-FM_i-xii.qxd 4/6/13 9:31 AM Page ii Clinical Neuroanatomy, Twenty-Seventh Edition Copyright © 2013 by McGraw-Hill Education. Install Mysql Module Php Windows Installation.

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To contact a representative, please e-mail us at MCGH267-FM_i-xii.qxd 4/6/13 9:31 AM Page iii For Wendy and Rosalie, new lights in my life. MCGH267-FM_i-xii.qxd 4/6/13 9:31 AM Page iv MCGH267-FM_i-xii.qxd 4/6/13 9:31 AM Page v MCGH267-FM_i-xii.qxd 4/6/13 9:31 AM Page vi MCGH267-FM_i-xii.qxd 4/6/13 9:31 AM Page vii Contents Preface xi S E C T I O N I BASIC PRINCIPLES S E C T I O N 1 1. Fundamentals of the Nervous System 1 General Plan of the Nervous System 1 Peripheral Nervous System 5 Planes and Terms 5 References 6 2. Development and Cellular Constituents of the Nervous System 7 Cellular Aspects of Neural Development 7 Neurons 7 Neuronal Groupings and Connections 11 Neuroglia 11 Degeneration and Regeneration 15 Neurogenesis 17 References 18 3. Signaling in the Nervous System 19 Membrane Potential 19 Generator Potentials 20 Action Potentials 20 The Nerve Cell Membrane Contains Ion Channels 21 The Effects of Myelination 22 Conduction of Action Potentials 23 Synapses 24 Clinical Illustration 3–1 24 Synaptic Transmission 26 Excitatory and Inhibitory Synaptic Actions 27 Synaptic Plasticity and Long-Term Potentiation 27 Presynaptic Inhibition 28 The Neuromuscular Junction and the End-Plate Potential 28 Neurotransmitters 29 Case 1 31 References 32 II INTRODUCTION TO CLINICAL THINKING 33 4. The Relationship Between Neuroanatomy and Neurology 33 Symptoms and Signs of Neurologic Diseases 33 Where is the lesion? 36 What is the lesion?